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Indication:

Myomin – Herbal Hormone Balancing Formula

Natural Herbal Supplement For Men and Women

• Balances excess hormone levels and normalizes hormonal systems

• Boosts formation of interferon interlukin-2 and tumor necrosis factor

• Regulates and alleviates discomfort

• Inhibits aromatase enzyme

• Aromatase Inhibitor for Estrogen-Dominant Disorders: Endometriosis, cysts, fibroids and breast cancer

• Work for both Men and Women

• Blocks estrogen

• Metabolize unhealthy estrogens and promote proper hormonal balance.

• Reduce the size and symptoms of myomas (fibroids) found in the breast, uterus, and ovaries

• Help promote shrinkage of tumors and cysts: excellent for Kidney, Liver Cysts, brain tumors

• Reduces estradiol levels

• Relief of menopausal symptoms

• Reduce abdominal fat

• Maintain good health in female organs such as the breasts, uterus and ovaries

• Safe and effective for those with osteoporosis, kidney, and liver problems.

• All natural, no preservatives, no sodium, no artificial colors, no yeast, no animal products.

Myomin is an all natural formula of Chinese herbs that has been shown to help metabolize unhealthy estrogens and promote proper hormonal balance. Studies show that it also inhibits aromatase, an enzyme that converts androgens (testosterone) into estrogen.

 In addition to that, it competes with estradiol at the estrogen receptors of target cells. This is why Myomin is so effective for estrogen-dominant condition such as cysts and fibroids.

The Benefits of Myomin

Hospital research has shown that Myomin helps to reduce the size and symptoms of myomas (fibroids) found in the breast, uterus, and ovaries. It is especially helpful when these conditions have been encouraged by estrogen dominance. Myomin can be effective for cysts in the thyroid, kidney, and liver. Plus, Myomin has proven to be safe and effective for those with osteoporosis, kidney, and liver problems.

Myomin: Aromatase Inhibitor for Estrogen-Dominant Disorders

The primary role of estrogen is the development of female sex characteristics. It is also an important hormone in childbearing women and in maintain bone strength. Estrogen also plays a role in cell activity. When estrogen is released, it passes directly into cells throughout the body, binds to receptors in the target cells, and initiates cell activity, determining how they will function for the rest of an individual's life. Because estrogen dictates important mechanisms such as protein production and cell division, it is vital to growth processes not just during puberty but in adult life. However, its role in signalling cells to divide and multiply can trigger and promote abnormal growth of estrogen-responsive tissues. Estrogen-dominant disorders such as endometriosis, cysts, fibroids and breast cancer result from this process. Treatment of these disorders, therefore, involves blocking the action of estrogen of the affected tissues.

There are two ways to block the action of estrogen. On is by attaching to its receptors (selective estrogen receptor modulation). This stops the signalling that triggers cell division in target tissues. Another method is aromatase inhibition, which reduces estrogen production by blocking its conversion from androstenedione and testosterone.

Myomin is an all-natural herbal formula that can perform both functions. It contains Aralia, Smilax glabra, Curcurma zedoria, and Cyperus rotundus. These herbs have been traditionally used for various female ailments and hormone related disorders. Aralia and Cyperus rotundus both can reduce estradiol. Cyperus is also effective against cervical endometriosis and cervical carcinoma. Additionally, Aralia has been found to be cytotoxic against several human cancer cell lines.

Myomin inhibits the aromatase enzyme

Aromatase is a key enzyme in the synthesis of estrogen. Specifically, it converts androstenedione into estrone and testosterone into estradiol. For instance, evidence shows that breast cancer and prostate cancer tissues overexpress aromatase. Inhibiting aromatase, therefore, plays an important role in suppressing the deleterious action of estrogen on hormone related conditions.

The aromatase inhibition mechanism is not only relevant to women but to men as well. Evidence supports the idea that elevated estrogen levels and aromatase expression in men can cause abnormalities, especially in the prostate. In men, estrogen is primarily synthesized in fat tissue. This is why men with metabolic conditions (e.g. diabetes) and high body mass index usually exhibit high serum estrogen levels. Some abnormalities that can result include undescended testis, low sperm count/quality, and decreased testosterone levels. There is also some proof that fetal exposure to environmental estrogens increases incidence of testicular cancer. Estrogen depletion and aromatase inhibition, therefore, are important therapies for men as well.

An in vivo study demonstrates that Myomin inhibits the aromatase enzyme in the ectopic endometrium and ovarian tissue of rats. Aromatase was expressed markedly in the untreated ectopic endometrium of the positive control group. On the other hand, aromatase expression significantly decreased in the ectopic endometrium of the Myomin group after 28 days.

Similar to the ectopic endometrium tissue, aromatase expression was remarkably high in the untreated ovaries of the positive control group. After 28 days of therapy with Myomin, aromatase expression was significantly reduced in the ovarian tissue.

Image analysis of both the ectopic endometrium and ovarian tissues yielded elevated armoatase expression in the positive control group (108.9 and 149.8, respectively) in both tissues. After administration with Myomin for 28 days, aromatase expression reduced to 34.7 in the endometrium and 47.0 in the ovary. This translates to a 100% reduction of aromatase expression in the endometrium and an 85.6% reduction in the ovary compared to the negative control group.

Myomin has three functions

• It inhibits the aromatase enzyme, effectively reducing estradiol levels by preventing the conversion of androgens to estrone and estradiol. This allows testosterone and estriol (the good estrogen) to accumulate. Aromatase inhibition has become a worthwhile target in many estrogen-dominant disorders

• It competes with estradiol at the estrogen receptors. This function is particularly effective in cases where estrogen receptors are fully stimulated (e.g. after HRT). Competing with estradiol prevents estradiol from binding to receptors. As a result, proliferation of cells is avoided and abnormal growth inhibited.

• In increase interferon (IFN) and interleukin-2 (IL-2). IL-2 induces the proliferation of immune cells, enhancing the body's ability to kill tumor cells. IFN stimulates natural killer cells and is active against tumors.

It is worth noting that, in the Chang Hai Hospital studies show that approximately 1% of the subjects taking Myomin experienced side effects such as nausea and bloating. These symptoms abate when Myomin dosage is reduced or when it is taken with meals.

Myomin reduces estradiol levels

One study performed at the Shanghai Medical School illustrates the effect of Myomin on estradiol levels of mice during pregnancy – a period when estradiol levels are especially high. Two groups of 12 mice each were used in the study. One group was used as the control. The other group was given Myomin beginning 15 days into pregnancy. Three days later (on the 18 th day of the study), the average estradiol level of the Myomin group was 7.22pg/ml, approximately seven tiems less than the control group. After 6 days of taking Myomin (on the 21 st day of the study), their average estradiol level was 8.81 pg/ml while it was 85.98 pg/ml for the control group.

In another study, 90 female mice were divided into three groups. Each group was then given Myomin for 30, 60 and 180 days, respectively. The average estradiol levels after each period was 50.6, 36.6, and 32.4 pg/ml, respectively. After 180 days, the estradiol level stabilised. These results demonstrate long-term use of Myomin reduces estradiol in such a way that it maintains around the normal level. No side effects were reporet in this study.

A human study involved 60 postmenopausal women with cysts and/or fibroids. Postmenopausal women were studied because their estradiol levels are more stable than those of premenopaual women. Initially, the average estradiol level was 74.52 pg/ml. After only 10 days on Myomin, their average estradiol level reduced to 38.84 pg/ml. The fibroids, cysts and associated pain gradually reduced.

Case of Study:

R.bernhoft, MD from WA, reports that a male patient in his 50s had a high estrogen level. After taking Myomin for about 3 months, his estrogen level returned to normal.

Myomin on various estrogen dominant disorders

A study from Chang Hai Hospital involved 75 cases of fibrocystic breasts (70 women ages 18 to 52 years old and 5 men ages 62 to 64 years old). Sixty five percent of the women were under 35 years old. 25 cases were in the control group while 50 cases were in the Myomin group. Results of the study revealed that, in 14 cases, the fibrocystic breast completely cleared after 1 month of taking myomin while, in 16 cases, the fibrocystic breast reduced 50% in size. Among the five men in the study, the cysts cleared completely in 3 cases. Complete results of the study are enumerated below

Overall the effective rate of Myomin is more than 60% compared to the control group's 12% rate. In the Myomin group, in 48 out of 50 cases, associated pain cleared or tremendously reduced (p value <0.05) while in the control group, pain reduced in only 12 out of 25 cases.

Case studies per Chi Interprise:

1. V. Vidov , ND from NY, has a 40 year old female patient who had a fibroid cyst the size of an egg. After only 3 months on Myomin, the cyst disappeared.

2. J. Fowler from FL has a 42 year old female client who had 6 nodules in the breast (2 big and 4 small ones), found through several mammograms. After 4 months on Myomin, all the nodules are gone. Her doctor couldn't believe it.

3. A 1994 clinical study was conducted on 255 patients with ovarian cysts and endometriosis. After 5 months, Myomin was effective on 147 patients (57%) while some improvements was observed in 87 patients (34.1%). No effect was observed in only 21 patients.

4. Another study was conducted on both pre- and postmenopausal women with ovarian cysts. In one study from the Chang Hai Hospital in Shanghai , China , 85 female patients with ovarian cysts were involved, with ages ranging from 27 to 64 years old (more than 50% of them between 34 and 45 years old). Out of the 85, 40 cases were related to endometriosis (hyatidiform cyst), 44 cases were simple ovarian cysts and 1 case of ovarian cancer. After 1 to 3 courses of the herbal formula, the cysts and symptoms of 15 patients completely cleared with no recurrence 3 months after the study. In 34 patients, the size of the cyst reduced by 50% and some of the associated symptoms were relieved.

5. Y. Dikansky, DDS from NY, has a 38 year old female patient with an ovarian cyst for 8 years. The cyst was 3.7x6x2. After 3 months on Myomin, the cyst cleared.

6. A 2000 study at the Shanghai Medical School was performed on 60 patients with small uterine fibroids. It revealed that if Myomin is used in combination with Revivin, it is 69.2% effective on uterine fibroids that exceed 2.5cm³ in size. Another alternative would be to combine Myomin with Angiostop, an angiogenesis inhibitor.

7. J.Stickel, DC from IA, reports on a patient with uterine fibroids and colon polyps. After taking Myomin for 3 months, her uterine fibroids and polyps had completely disappeared.

8. W. Stimack, NMD from IN, has a 29 year old female patient with 12 fibroids that made her appear 8 months pregnant. The fibroids cleared after 5 months on Myomin.

The applications of aromatase inhibitors in many health conditions are continually increasing today. They have been shown to reduce the risk of recurrent breast cancer especially when used for a longer period. However, the aromatase inhibitor drugs in the market today are indicated for postmenopausal women only. This is very limiting especially since more and more premenopausal women are developing estrogen-related conditions. It is for this reason that the results of these studies on Myomin are significant. As stated in an earlier section, Myomin has been used in clinical studies and found to be effective in both premenopausal and postmenopausal women with ovarian cysts, fibrocystic breast and endometriosis as well as in men with fibrocystic breast. It is able to produce these favorable results by inhibiting aromatase and consequently reducing estrogen levels.

Aromatase inhibition is important in men as well. As men age, testosterone is being more readily converted to estrogen through the aromatase enzyme. Increased estrogen levels can lead to problems such as prostate cancer, prostatitis, and even gynecomastia. Evidence suggests that local aromatase expression in the prostate increases in malignancy. In fact, the level of aromatase expression in malignant prostate tissue is comparable to that in breast cancer tissue. As a result, local estrogen levels are also promoted at the prostate tumor site, increasing growth. Aromatase inhibitors like myomin will help block the action of aromatase, thereby minimizing the depletion of testosterone and reducing estrogen levels.

Cases Reported:

1. A.Schwartz, DC from PA, reports on a 2.5 year old boy with very rare Type 2 neurofibromatosis. Two were found in the brain when he was one year old and another one was found in March 2003. Then he took Myomin (weight dependant). Three months later, his MRI showed that the neurofibromatosis has established. No Angiostop and Revivin were given because the patient was too young.

2. M. McCain , ND from AR, states: “Myomin has proven exceptional in reducing hard to dissolve fibroid tumors and liver and kidney cysts. We have many remarkable testimonials.”

3. J.Fowler from FL has a 24 year old male client with a cyst on his testicle. With Myomin, it went away. He says, “Dr.Chi saved my life!”

4. S. Young , ND from CO, has the following reports:

5.  A 38 year old female patient had a colloid cyst on her thyroid. Her regular MD wanted to give her prescriptions to shut down her thyroid “and see what would happen.” She tried Myomin instead and the cyst melted away in 3 weeks.

6.  Another patient had adhesive scar tissue in his lungs, for which she recommended myomin, etc. After about 7 months, he is able to breathe and sleep again without pain. He is now able to exercise freely and take deep breaths with only one small area of pain. His ability to rest and sleep has improved tremendously.

7. Jack Wise, ND from OK, has a 42 year old female patient with polycystic kidney disease, which progressed into kidney failure. She had whole body edema. After using Myomin, Asparagus Extract and Bathdetox, she is 99% better clinically.

8.  K. Hajduk , DC from CA, reports on a 50 year old male patient whose PSA level was 7.9. He recommended that the patient take Myomin, Revivin and use the MIT once a day. After 4 months, the patient's PSA dropped to 2.

Myomin may also offer relief of menopausal symptoms

Myomin has also been reported to be effective in reducing the severity and frequency of hot flashes in some women. Although its exact mechanism on this particular function remains to be elucidated, it may be explained by Myomin's ability to compete with estrogen at the cells' estrogen receptors. It should be noted, however, that some women experience worsening of symptoms with Myomin. This is probably due to very low levels of estrogen in these women.

Myomin Success Stories:

1. Thu Le from WA has a 50 year old menopausal client who experienced hot flashes, cold sweats, and irregular sleeping habits. Within a week of taking myomin, her symptoms reduced by 50%. Now she's so thankful for Myomins effects on her.

2. B.C. from CA also experienced similar results. She has had hot flashes since she started menopause. But after taking only a minimal dose of Myomin, she does not experience any hot flashes anymore.

3. Robin Welch, DC from CA, has a 47 year old female patient who had hot flashes and sleeping problems from 5 years. Chi-F and Myomin were recommended for her. On the first day, she could already fell a difference. After a month on the supplements, she could sleep well and her hot flashes have been eliminated.

4. D.B., RN from VT, used natural progesterone in 1999. After 3 years, she developed fibroids. She then used DIM for a few weeks but had headaches and hot flashes. In Sept 2005, she added Myomin. In May 2006, she added Revivin, Angiostop. Now all her fibroids are gone.

Myomin for Abdominal Fat

An aromatase inhibitor like Myomin can also reduce abdominal fat. Abdominal obesity is associated with decreased testosterone levels (or hypogonadism) and increased estradiol levels. Hypogonadism leads to the deposition of fat in the abdomen. As fat accumulates, aromatase activity increases at the site, causing more testosterone to be converted into estradiol. Taking testosterone or DHEA supplements is not enough because if aromatase is uncontrolled, then testosterone and DHEA will eventually be converted to estradiol. Adding an aromatase inhibitor like Myomin blocks the action of aromatase, effectively preventing the testosterone from being converted into estradiol. This leads to more muscle mass and the loss of abdominal weight.

Case of Studies:

1. T.M. a 47 year old male from NY, took Myomin for 4 months and followed a proper diet. He reduced his weight from 220 to 195lbs and has lost 2 inches around his waist.

2. C.H., PhD from CA, has a 52 year old patient who reduced his total body fat from 32% to 16% after 5months on Myomin.

Specification:

120 Capsules / Bottle, 400 mg / Per Capsule

Supplement Facts

Amount per Serving - Two capsules contain:

• 200 mg - Smilax glabra Roxb.

• 200 mg - Curcuma zedoria

• 200 mg - Cyperus rotundus

• 200 mg - Aralia Dasyphylla Mig.

Daily Value not established for these ingredients. Contains no preservatives, no sodium, no artificial colors, no yeast, no animal products. All natural. Keep out of reach of children.

Direction:

As a dietary supplement, take 2 to 3 capsules per use, 2 to 3 times a day after meals, or as directed by your health care practitioner.

Storage:

Keep bottle tightly closed.

Warning:

Keep out of reach of children.

Disclaimer:

This statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any  disease.